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Power tends to corrupt and absolute power corrupts absolutely. Lord Acton (1834 - 1902)
  Mental Healthcare Politics and Research Power tends to corrupt and absolute power corrupts absolutely. Lord Acton (1834 - 1902)Introduction Ã There is a big battle going on over universal healthcare. The Republicans claim that this is socialized medicine . As usual anything designed to help the poor is called socialism . However,these same Republicans don't call the public schools socialized schools or the public libraries socialized libraries . Public schools give free education to all kids. Public libraries lend books forfree to everybody. Ã All of this does not mean that there will be no problems with universal healthcare. The drugcompanies may not like it because they may no longer be able to gauge people with absurdly highprices. Some doctors may not like it because they may not be able to charge as much. However,there are very serious problems with our current system. Hospitals have been closing. Nursinghomes have been going out of business. Ã Elderly people can't afford dental care. The poor can't afford dental care. Medicare doesn'tcover it.Mental Healthcare Ã There are disastrous problems in mental healthcare. Many people are homeless, often withsubstance abuse. Many people who probably should be in state hospitals are on the streets. But whatare the answers? Do they cost more money, or less? The answer may be less. Orthomoleculartreatment is cheaper, safer, and more logical than xenobiotic treatment (drugs).Drugs Similarly, it is unclear whether the neuropathological features relate primarily to the therapeuticaction of antipsychotics or, more likely, to their predisposition to cause tardive dyskinesia and othermotor side-effects. Ã Harrison PJ.University Department of Psychiatry, Warneford Hospital, Oxford, UK.  Ã The quote is from Ref. 1. It seems that these drugs cause neuropathology. This has been shownin studies with rats. This makes neuropathology studies of patients more difficult. One way to getaround this is to look at old neuropathology studies of patients before the drugs were invented.Harrison himself, an Oxford scientist, did a little of this in Ref. Most installed pumps were notsrcinally sourced for their current use. Typically, a line in a facility is moved and the pump thatonce providedcooling water to an injection molding machine is now asked to move oil from a rail carto a tank. Sadly, this causes quite a few problems for the pump and the plant. Pumps operate wherethe pump curve crosses the system curve. When you relocate a pump from one system to another,this means that the system curve is different. This new system may cause the pump to operate away  from its best efficiency point, leading to vibration and other component failures that are simplysymptoms of a mis-matched pump and system.2. However, most of the studies he reviewed in Ref. 2were done after the advent of psychiatric drugs. Neuroleptic drugs came out in 1952. The first onewas Thorazine. Ã One such study is Ref. 3 where Southard, a Harvard scientist, reported lesions and anomalies in dementia praecox , which is what schizophrenia was called at the time. These abnormalities werein the cortex. Southard found rotary pump gliosis, fat deposits, etc. Aside from the left-sidedness of the lesions and internal hydrocephalus, very striking is thepreference of these changes to occupy the association centres of Fleschig. Southard (3)Ã Research Ã Refs. 4 & 5 describe some of the research that has been going on. Stevens (1982), in keeping with observations going back as far as Alzheimer (Nieto and Escobar,1972; Fisman, 1975), found fibrillary gliosis (reactive astrocytosis) in ~70% of her cases of schizophrenia. The gliosis was usually located in periventricular and subependymal regions of thediencephalon or in adjacent basal forebrain structures. As gliosis is a sign of past inflammation(Kreutzberg et al., 1997), this finding supported a number of aetiopathogenic scenarios forschizophrenia involving infective, ischaemic, autoimmune or neurodegenerative processes. Harrison (2) Ã The main theory is that schizophrenia is a neurodegenerative disease. There was adevelopmental theory, but it has been repeatedly proven wrong by longitudinal studies that showprogressive brain tissue loss in schizophrenia. Averback (1981) Ã In 1981 Dr. Paul Averback published two brilliant articles on the neuropathology of schizophrenia. The second one confirmed and extended the first one (7). The second one reportedadditional lesions that were similar in the nearby septal area of the brain. The nucleus of the ansa peduncularis in the substantia innominata frequently contains degeneratingneurons in patients with Huntington's disease, Alzheimer's disease, schizophrenia, and possiblyother neurological and neuropsychiatric conditions. Ã Paul Averback, MD (7) The cells show massive distention with solvent-extractable lipid-pigment vacuolar droplet materialthat imparts a distinctive light and electron microscopic appearance. Averback (7) Ã The septal area had been previously suspected byÃ Dr. R. G. Heath of New Orleans due toabnormal depth EEG readings from that area. Thus Averback's work confirmed Heath. Ã Averback reported that the Nissl bodies were barely recognizable .Ã This gives us a veryimportant clue, although Averback himself didn't make much of it. The Nissl bodies store aminoacids for the manufacture of proteins. If one or more amino acids were flooding the cells, much of  Averback's findings would be explained. Excessive amino acids could destroy the Nissl bodies. Somecould be converted to fat, which would explain the fat vacuoles. They could increase the cell's  metabolic rate, which would explain the lipofuscin. Amino acids flooding the cells could cause thecells to bloat and to even burst. A Website for the Layman Ã Much of the information that I present is on an academic level. However, there is a very goodwebsite on mental health which provides information for the layman. THis website is called HealthyPlace , and it has aÃ URL of Ã But what is the treatment, or what are the treatments? My recommendation is orthomoleculartreatments. If your brain is allergic to certain amino acids, and since amino acids are found in thediet, wouldn't it make sense to avoid the substances that you are allergic too? However, it may bemore complicated than this. Sugar has the effect of pumping more tryptophan into the brain.Tryptophan is an amino acid. Therefore sugar needs to be restricted.Ã  Ã Refs. 11-13, which are available free full text on the Internet, explain horizontal centrifugalpumps more about orthomolecular psychiatry.Ã References1. The neuropathological effects of antipsychotic drugs.Harrison PJ.Schizophr Res. 1999 Nov 30;40(2):87-99. Review.2.Ã The neuropathology of schizophrenia. A critical review of the data and their interpretation.Harrison PJ.Brain. 1999 Apr;122 ( Pt 4):593-624. Review.3. Southard EE. On the topographical distribution of cortex lesions and anomalies in dementiapraecox, with some account of their functional significance. Am J Insan 1915; 71: 603âEUR 71.4. Roy, P. D., Zipursky, R. B., Saint-Cyr, J. A., et al (1998) Temporal horn enlargement is present inschizophrenia and bipolar disorder. Biological Psychiatry, 44, 418 -422.5. Schildkraut, J. J. (1965) The catecholamine hypothesis of affective disorders: a review of supporting evidence. American Journal of Psychiatry, 122, 509 -522.6. Stevens JR. Neuropathology of schizophrenia. Arch Gen Psychiatry 1982; 39: 1131âEUR 9.7. Averback P. Lesions of the nucleus ansae peduncularis in neuropsychiatric disease. Arch Neurol1981; 38: 230âEUR 5.8. Mettler FA: Anatomy of the basal ganglia, in Vinken PJ, Bruyn GW (eds): Handbook of ClinicalNeurology. Amsterdam, North Holland Publishing Co, 1968, pp 1-55.  9. Mettler FA: Neuroanatomy. St Louis, CV Mosby Co, 1948, pp 355-384.10. Wolman M: Pigments in Pathology. New York, Academic Press Inc, 1969.11.Ã Ã
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