Properties of Biofilm

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Properties of Biofilm
  PROPERTIES OF BIOFILM Presented by Dr Krishna Das PG Student  Concept Of Biofilm ã In nature, bacteria have to struggle to obtain sufficient nutrients to support growth and have to compete with other microbial communities containing many different species, sometimes a hundred or more, sharing the same site. ã Nutrients tend to concentrate at interfaces, and consequently the densest bacterial populations are located at interfaces of various kinds. ã Eg. Solid-liquid boundaries, solid-gas interface (needs moisture or dies of desiccation)  ã  The human body provides several interfaces that support microbial populations, of which the most important in healthy individuals are the skin , gut , mouth , and female urogenital tract. ã The oral cavity is somewhat unique in this regard since it provides hard, non shedding surfaces (teeth) that are accessible for microbial colonization. ã The first description for microbial colonization in oral cavity dates back to the 1683 when Anton Von Leeuwenhoek - the inventor of the Microscope, saw microbial aggregates on scrapings of plaque from his teeth.  ã The importance of surfaces for microbial growth was recognized as early as the 1920s, when a number of workers independently noted that bacteria growing on glass slides submerged in soil were different from those that could be cultured in broth. ã However, it was not until around 50 years later that sessile microbial populations were considered to be sufficiently different from free-living microorganisms to merit their own name, and the term “ BIOFILM ”  was coined. (Bill Costerton in 1978). ã Biofilms are composed of microbial cells encased within a matrix of extracellular polymeric substances (EPS) such as polysaccharides, proteins, and nucleic acids.
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