Documents

Thesis Report

Categories
Published
of 3
All materials on our website are shared by users. If you have any questions about copyright issues, please report us to resolve them. We are always happy to assist you.
Related Documents
Share
Description
Good morning I, am Tugon, Remon Matias and together with my groups mates Adun, Nurwalid Carlos, Jarell Reiz Resplandor, Lean Andrew Hermenegildo, Jovelyn Resma, Richard Niel We will be presenting you our thesis research about the anti-inflammatory activity of the flavonoid extracts from the mesocarp of Cucurbita citrullus linn. Introduction What is inflammation?  Is the body’s response to injury To be more specific  It is the body’s attempt to self protection to remove
Transcript
  Good morning I, am Tugon, Remon Matias and together with my groups mates   Adun, Nurwalid Carlos, Jarell Reiz Resplandor, Lean Andrew   Hermenegildo, Jovelyn Resma, Richard Niel We will be presenting you our thesis research about the anti-inflammatory activity of the flavonoid extracts from the mesocarp of Cucurbita citrullus linn. Introduction What is inflammation?    Is the body’s response to injury  To be more specific    It is the body’s attempt to self protection to remove harmful stimuli including damage cells, irritants, or pathogens, and begin the process of healing There are two types of inflammation>    Acute inflammation and Chronic inflammation Acute inflammation is referred to as:    A short term inflammation. It starts rapidly (rapid onset) and quickly becomes severe for few days. The common cause of acute inflammation is tissue injury      Whenever there is injury, there is a acute inflammation, and it can be manifest by 5 cardinal signs, heat, warmth, swelling, pain and loss of function Chronic inflammation in the other hand is referred to as:    A long term inflammation. It may resulted to the Failure to eliminate whatever was causing an acute inflammation or an autoimmune response to an antigen, wherein the immune system attacks healthy tissue, mistaking it (them) for harmful pathogens.   Here are the common examples of chronic inflammation: Common Examples of: Rheumatoid Arthritis, Chronic Periodontitis , Ulcerative colitis, Chronic peptic ulcer,.etc.  There are certain drugs that can manage inflammation: namely: NSAIDs or Non-steroidal anti-inflammatory drugs, Acetaminophen or commonly known here in the Philippines as paracetamol, and corticosteroids.  Among the three the commonly used drug for inflammation is the NSAIDs. It acts by counteracting the COX enzyme which synthesizes prostaglandins that creates inflammation. To give you a clear idea. inflammation is produce when our body’s arachidonic acid is synthesized to prostaglandins by the Cyclooxygenase (COX) enzyme. These prostaglandins are responsible for the production of inflammation. NSAIDs act by suppress inflammation by inhibiting the COX enzyme thus prevents the conversion of arachidonic acid to prostaglandins. However there if these drugs are to be used in long term… it can l ead to severe adverse reaction such as stomach ulcers or life threatening hemorrhage… it may also worsen asthma conditions and cause kidney damage… It can also increase the risk of stro ke and myocardial infraction Thus our group aims to develop an develop an alternative medicine which include the use of plant constituents as they display a lesser side effects   Establish a drugs that are more accessible to the under-privileged of the society   Lastly, To improved the health status of the population Our group is focused in certain plant constituents which is the flavonoids:   Flavonoids Are low molecular weight, bioactive polyphenols, which plays a vital role in photosynthesizing in plant They can inhibit inflammation by, just like NSAIDs It inhibits the COX enzymes which synthesizes prostaglandins that creates inflammation Here are the schematic diagram on how we initiated our research…  We are going to develop an alternative medicine using a fruit extract that wil act as medicine and supplement that will be used as therapy for inflammation… the fruit we going to used is cucurbita citrullus linn and we going to utilize its flavonoid extrac and use it as therapy for inflammation. Our general objective is To determine the anti-inflammatory activity of the flavonoid extract from the mesocarp of Cucurbita citrullus Linn Our specific objective are the following:   What are the constituenst present on the mesocarp of the Cucurbita citrullus Linn?     What is the amount of Flavonoid present in the mesocarp of Cucurbita citrullus Linn?     What is the physical and chemical and structural properties of the favonoid extract from the mesocarp of Cucurbita citrullus Linn?      What is the approximate lethal dose of flavonoid extract of the Cucurbita citrullus Linn?     What dose of the flavonoid extract of the mesocarp of Cucurbita citrullus Linn exhibits anti-inflammatory activity?   How does the anti-inflammatory activity of the flavonoid extract differ from the mesocarp of Cucurbita citrullus Linn  differ from the prototype NSAID drug aspirin?

microwave

Jul 23, 2017

Amos Moshell

Jul 23, 2017
We Need Your Support
Thank you for visiting our website and your interest in our free products and services. We are nonprofit website to share and download documents. To the running of this website, we need your help to support us.

Thanks to everyone for your continued support.

No, Thanks